FIG 2.

Plasma viral loads in rhesus macaques pretreated with different doses of PGT121 and 3BNC117 and challenged with SHIV-327c. SHIV RNA levels are shown for animals that received 10 mg/kg PGT121 (A), 2 mg/kg PGT121 (B), 10 mg/kg 3BNC117 (C), and 2 mg/kg 3BNC117 (D) or PBS control (E). All animals treated with PBS-control became infected. Sterilizing immunity was observed in all animals given 10 mg/kg PGT121, in two of three animals given 2 mg/kg of PGT121, and in one of four animals given 10 mg/kg 3BNC117. (F) Time in days from challenge to the first detectable SHIV RNA in plasma Shown are means ± SEM.