FIG 5.
Sliding-window analyses of dN/dS ratio and Kyte-Doolittle hydropathy score along the open reading frame sequences of L genes from a total of 15 representative RABV strains (A and B) or 12 lyssavirus species (C). Solid red and blue lines show the average values for dN/dS ratio and hydropathy score, respectively, in a window composed of 20 codon sites. The red and blue longitudinal bars on the solid lines show the standard deviations of dN/dS ratio and hydropathy score, respectively. Dashed red and blue lines show the average value for dN/dS ratio (0.07 in RABVs and 0.15 in lyssaviruses) and cutoff value for hydrophobic (hydropathy score > 0) and hydrophilic (hydropathy score < 0) regions, respectively. Yellow bars represent CRs I to VI. Blue bars indicate the regions with low values for dN/dS ratio and hydropathy score revealed in this study. aa, amino acids.