TABLE 3.

Peptide design^a

^a15-mer peptides overlapping by 11 amino acids were constructed for the reference STLV-1 genome, the full-length genome of a baboon isolate of STLV-1 from the NCBI database (GenBank accession number JX987040.1). Using the sequences isolated from T cell lines of animals 12141 and 12752, variant peptides were generated for any region whose sequence varied from the reference Tax sequence. These differences were pooled as indicated by the outlined sequences. Blue, peptide pools tested for animal 12752; green, peptide pools tested for animal 12141. When both animals possessed the same mutations, this was indicated by the text “SAME as 12752.” By comparison of the reference and variant peptide pools, it was possible to determine if the mutations had any impact on the immunogenicity of that epitope. Sub, subset.