Fig. 8.

Effects of liraglutide on NO production under hyperglycemic conditions. HUVECs were cultured in normal (5.5 mmol/L) or high-glucose (25 mmol/L) medium 48 h prior to the experiments; a NO production 2 h after vehicle or liraglutide (10 nmol/L) stimulation under normal or high glucose conditions, n = 4–6; b representative western blot images of HUVECs cultured in high-glucose, stimulated with vehicle or liraglutide (10 nmol/L) for 20 min, and the ratio of p- to t-LKB1 (c), AMPK (d), and eNOS (e), n = 6–8; *p < 0.05; **p < 0.01