Figure 3.

Overall survival of patients with pancreatic adenocarcinoma according to circulating biomarkers at baseline. (A) Kaplan–Maier survival curve stratified by the presence (black line) or absence (red line) of CTCs. (B) Kaplan–Maier survival curve stratified by the CTC level above (black line) or below (red line) the median value (4 CTC ml⁻¹). (C) Kaplan–Maier survival curve stratified by the presence (black line) or absence (red line) of ctDNA. (D) Kaplan–Maier survival curve stratified by the ctDNA level above (black line) or below (red line) the median allelic frequency value (0.75%). (E) Kaplan–Maier survival curve stratified by the cfDNA level above (black line) or below (red line) the median value (59.5 ng ml⁻¹) expressed as ng ml⁻¹ of plasma. (F) Kaplan–Maier survival curve stratified by the CA19.9 level above (black line) or below (red line) the median value (174 UI l⁻¹).