Table 5. Time to distant metastasis in patients with primary cutaneous melanoma by four different metastatic pathways.

Metastatic pathway	Median time to distant metastasis (months)	IQR (months)	P-value
Pathway 1 Development of satellite or in-transit metastases followed by regional lymph node metastases and distant metastases	15	(9, 17)	0.4
Pathway 2 Development of satellite or in-transit metastases followed by distant metastases	16	(7, 26)	–
Pathway 3 Development of regional lymph node metastases followed by distant metastases	18	(10, 27)	–
Pathway 4 Development of distant metastases as first tumour recurrence	15	(7, 28)	–
Total	16	(9, 26)	–

Abbreviation: IQR=interquartile range.