Figure 3.

miR-29c expression correlates with glioma grades and patients’ prognoses. (A) Representative images of miR-29c ISH detection. Scale bar, 50 μm. (B) Comparisons among groups of miR-29c expression level (Labelling index, LI (%)) in the above FFPE samples. The miR-29c LI (%) of each sample was calculated as described in Figure 1. The data in B are presented as the mean±s.d. ***P<0.001. (C and D) Kaplan–Meier analyses of the correlation between miR-29c and DFS (upper) or OS (under) of all grade glioma patients (C) and WHO grade IV glioblastoma patients (D). Patients were stratified into high and low expression subgroups using the median of miR-29c LIs.