Table 1. Patient tumour and treatment characteristics (N=326).
Patient age group
|
||||||||
---|---|---|---|---|---|---|---|---|
70–74yrs
|
75–84yrs
|
⩾85yrs
|
All patients
|
|||||
Tumour and treatment characteristics | N | % | N | % | N | % | N | % |
T stage
| ||||||||
T1 | 49 | 43% | 78 | 44% | 12 | 43% | 139 | 43% |
T2 | 51 | 44% | 67 | 38% | 16 | 41% | 134 | 41% |
T3 | 9 | 8% | 17 | 10% | 2 | 9% | 28 | 9% |
T4 | 0 | 0% | 3 | 2% | 0 | 1% | 3 | 1% |
Unknown | 6 | 5% | 12 | 7% | 4 | 7% | 22 | 7% |
N stage
| ||||||||
Node + | 33 | 29% | 58 | 33% | 10 | 31% | 101 | 31% |
Node − | 76 | 66% | 108 | 61% | 22 | 63% | 206 | 63% |
Node status unknown | 6 | 5% | 11 | 6% | 2 | 6% | 19 | 6% |
Grade
| ||||||||
I | 12 | 10% | 21 | 12% | 6 | 12% | 39 | 12% |
II | 71 | 62% | 85 | 48% | 18 | 53% | 174 | 53% |
III | 30 | 26% | 68 | 38% | 10 | 33% | 108 | 33% |
Unknown | 2 | 2% | 3 | 2% | 0 | 2% | 5 | 2% |
Histology
| ||||||||
IDC | 81 | 70% | 151 | 85% | 27 | 79% | 259 | 79% |
ILC | 23 | 20% | 13 | 7% | 3 | 12% | 39 | 12% |
Other | 5 | 4% | 5 | 3% | 1 | 3% | 11 | 3% |
Unknown | 6 | 5% | 8 | 5% | 3 | 5% | 17 | 5% |
Receptor status
| ||||||||
ER status | ||||||||
ER+ | 104 | 90% | 153 | 86% | 28 | 87% | 285 | 87% |
ER− | 11 | 10% | 24 | 14% | 6 | 13% | 41 | 13% |
HER2 status | ||||||||
HER2+ | 15 | 13% | 27 | 15% | 4 | 14% | 46 | 14% |
HER2− | 95 | 83% | 144 | 81% | 28 | 82% | 267 | 82% |
Unknown | 5 | 4% | 6 | 3% | 2 | 4% | 13 | 4% |
Surgery
| ||||||||
Mastectomy | 41 | 36% | 56 | 32% | 10 | 29% | 107 | 33% |
WLE | 70 | 61% | 113 | 64% | 22 | 65% | 205 | 63% |
No surgery at all | 4 | 3% | 6 | 3% | 2 | 6% | 12 | 4% |
Unknown | 0 | 0% | 2 | 1% | 0 | 0% | 2 | 1% |
Axillary surgery | 102 | 89% | 159 | 90% | 26 | 76% | 287 | 88% |
Adjuvant radiotherapy
| ||||||||
Yes | 79 | 69% | 125 | 71% | 25 | 74% | 229 | 70% |
No | 32 | 28% | 50 | 28% | 9 | 26% | 91 | 28% |
Unknown | 4 | 3% | 2 | 1% | 0 | 0% | 6 | 2% |
WLE+adjuvant radiotherapy | 63 | 90% | 103 | 91% | 19 | 86% | 185 | 90%a |
Adjuvant chemotherapy
| ||||||||
Yes | 17 | 15% | 40 | 23% | 8 | 24% | 65 | 20% |
No | 95 | 83% | 136 | 77% | 26 | 76% | 257 | 79% |
Unknown | 3 | 3% | 1 | 1% | 0 | 0% | 4 | 1% |
HER2-positive patients receiving Trastuzumab+Chemotherapyb | 7 | 47% | 18 | 67% | 4 | 100% | 29 | 63% |
Endocrine therapy
| ||||||||
ER-positive patients receiving adjuvant endocrine therapy | 95 | 91% | 137 | 90% | 27 | 96% | 259 | 91% |
Abbreviations: ER=oestrogen receptor; HER2 = human epidermal growth factor receptor 2; IDC= Infiltrating ductal carcinoma; ILC= Infiltrating lobular carcinoma; WLE=wide local excision.
90%=185 of the 205 patients who underwent WLE and subsequently received adjuvant radiotherapy.
Four patients received Trastuzumab without concomitant chemotherapy: 1 in the 70–74 years age group, 2 in the 75–84 years age group, and 1 in the ⩾85yr group.