Table 1.
Rabies vaccination protection following an intra-cranial challenge in mice
| Total number of mice | Survival after challenge with | ||
|---|---|---|---|
| FIRD-RABV n (%) |
FI-EBLV-2 n (%) |
||
| Rabies Imovax, vaccinated twice | 20 | 20 (100) | 16 (80) |
| P value1 | 0.000 | 0.002 | |
| Rabies Imovax, vaccinated once | 20 | ND | 15 (75) |
| P value1 | 0.005 | ||
| Virus control 50 MLD50 | 5 | 0 (0) | 0 (0) |
| Virus control 5 MLD50 | 5 | 2 (40) | 2 (40) |
| Virus control 0.5 MLD50 | 5 | 4 (80) | 4 (80) |
| Rabisin, vaccinated once | 20 | 20 (100) | 16 (80) |
| P value1 | 0.002 | ||
| Virus control 50 MLD50 | 5 | 0 (0) | 0 (0) |
| Virus control 5 MLD50 | 5 | 2 (40) | 2 (40) |
| Virus control 0.5 MLD50 | 5 | 3 (60) | 4 (80) |
1P value derived using Fisher’s exact test for the number of vaccinated and challenged mice that survived relative to the total and compared with the 50 MLD50 virus control mice