Table 1.

S.agalactiae Sputum Isolates and Exacerbation Status in Adult Cystic Fibrosis Patients

Isolate	Patient	Date of Isolation	CFUa	GBS Most Abundant	Reduced FEV1 b	PExc *	ABx Required	Co-Infectionsd
1	1	1990	104	N	N	Y	Y	HI
2	2	2005	104	N	N	N	–	PA
3	3	1994	106	N	Y	Y*	Y	MSSA, SM
4	4	2013	106	Equal	N	N	–	PA
5	5	2012	106	N	N	Y	Y	PA
6	5	−2012	104	N	Y	N	–	PA
7	5	−2012	105	N	N	N	–	PA
8	5	2012	106	Equal	N	N	–	PA
9	5	2013	N/A	Equal	Y	N	–	PA
10	5	2013	105	N	N	N	N	PA
11	5	2013	106	N	N	Y	Y	PA
12	5	2013	107	Y	Y	Y*	Y	PA
13	6	1992	105	N	N	N	–	PA, MSSA
14	7	1986	104	N	N/A	Y*	Y	PA
15	7	1986	N/A	Y	N	N	–	–
16	7	1986	N/A	Y	N	N	–	–
17	7	1987	106	N	N	N	–	HI
18	7	1987	105	N	Y	N	–	O
19	7	1987	105	N/A	N	N	–	N/A
20	7	1987	104	N	N	N	–	–
21	8	2011	105	Equal	N	N	–	MSSA
22	9	2013	106	Y	N	N	–	–
23	10	2013	106	Equal	N	N	–	MSSA
24	11	1990	105	N	N	Y	Y	PA
25	11	1991	106	Y	N	N	–	PA
26	11	1992	106	Equal	N	N	–	PA
27	11	1992	104	Equal	N	Y	Y	PA
28	11	1993	108	Y	N	Y	Y	PA
29	11	1993	107	N	N	N	–	PA, O
30	11	1993	107	Equal	N	N	–	PA, O

^aCFU = colony forming units

^bReduced FEV1 = reduction in reduction in FEV₁ by >10% and/or >200cm³ at time of isolate compared to baseline FEV₁

^cPEx = pulmonary exacerbation as defined by Fuch’s Criteria and/or need for antibiotics

^*Severe PEx = pulmonary exacerbation requiring intravenous antibiotics and/or hospitalization

^dHI: Haemophilus influenza, PA: Pseudomonas aeruginosa, MSSA: Methicillin sensitive S. aureus, SM = Stenotrophomonas maltophilia, S.marcecens = Serratia marcecens, Bc: Burkholderia cenocepacia, CA: Candida albicans, O: other N/A = Not available N = No Y = Yes