Table 3.

Preliminary physicochemical characterization data for activated pneumococcal polysaccharides and monovalent pneumococcal conjugates prepared using in vacuo glycation.

Serotype	Activated PS MW (kDa)	Conjugate MW (kDa)	PS:Protein ratio	Free protein (%)	Appearance	Soluble
1	>100	690	<10	<1	Clear & colorless	+
3	>100	650	<10	<1	Clear & colorless	+
4	>100	320	<10	<1	Clear & colorless	+
5	<100	250	<10	<1	Clear & colorless	+
6A	<100	320	<10	<1	Clear & colorless	+
6B	>100	200	<10	<1	Clear & colorless	+
7F	<100	340	<10	<4	Clear & colorless	+
9V	>100	240	<10	<1	Clear & colorless	+
14	>100	300	<10	<1	Clear & colorless	+
18C	>100	440	<10	<1	Clear & colorless	+
19A	<100	640	<10	<1	Clear & colorless	+
19F	<100	700	<10	<1	Clear & colorless	+
23F	<100	270	<10	<9	Clear & colorless	+