Table 4.
Effects of COE on serum lipid profile in diabetic model mice after 4 weeks of treatment.
Groups | TG (mmol/L) | TC (mmol/L) | HDLC (mmol/L) | LDLC (mmol/L) |
---|---|---|---|---|
NC | 1.03 ± 0.38∗∗ | 1.81 ± 0.41∗∗ | 2.34 ± 0.24∗∗ | 0.20 ± 0.05∗∗ |
DM | 2.06 ± 0.43ΔΔ | 3.27 ± 0.23ΔΔ | 1.28 ± 0.36ΔΔ | 0.44 ± 0.09ΔΔ |
COE-L | 1.64 ± 0.23∗∗Δ | 2.40 ± 0.47∗∗ | 1.52 ± 0.37ΔΔ | 0.32 ± 0.09∗∗ΔΔ |
COE-H | 1.35 ± 0.23∗∗ | 2.35 ± 0.52∗∗ | 2.17 ± 0.28∗∗ | 0.23 ± 0.06∗∗ |
ROS | 1.34 ± 0.53∗∗ | 2.14 ± 0.90∗∗ | 2.09 ± 0.45∗∗Δ | 0.27 ± 0.06∗∗ |
Data were presented as mean ± standard deviation (n = 8). TG: triglyceride; TC: total cholesterol; HDLC: high-density lipoprotein cholesterol; LDLC: low-density lipoprotein cholesterol. Mice were supplemented with COE at 50 (COE-L) or 200 (COE-H) mg/kg body weight and rosiglitazone at 4 mg/kg body weight (ROS) for 4 weeks. ∗∗P < 0.01 compared to group DM; ΔP < 0.05 and ΔΔP < 0.01 compared to group NC.