Table S5.

Genes involved in arsenic biotransformation and detoxification in C. eustigma, C. reinhardtii, V. carteri, Co. subellipsoidea, Ch. variabilis, Cy. merolae, and G. sulphuraria

Function	Gene	C. eustigma	C. reinhardtii	V. carteri	C. subellipsoidea	C. variabilis	C. merolae	G. sulphuraria
Arsenate reduction	ArsC	g12378.t1	—	—	XP_005649501	—	—	—
	ACR2	g7825.t1	XP_001689547	FD885985 (EST)	XP_005647416	XP_005849477	—	—
			XP_001692614
			XP_001702069
	Grx CPYC	g1236.t1	XP_001702999	XP_002956386	XP_005648436	XP_005849675	—	—
		g1239.t1	XP_001694001	XP_002947896	XP_005648435	XP_005846228
		g2117.t1
	Grx CPYC+DUP	g6358.t1	XP_001698084	XP_002946266	XP_005647340	XP_005845067	—
		g7910.t1
	Grx CGFS	g2788.t1	XP_001702880	XP_002955066	XP_005643530	XP_005844072	XP_005537122	XP_005704081
		g2918.t1	XP_001703697	XP_002948509	XP_005649414	XP_005844119	XP_005538021	XP_005703551
		g10539.t1	XP_001700896		XP_005652359	XP_005845214
		g11890.t1	XP_001689744			XP_005848188
		g13815.t1
	Grx CXX(C/S)	—	—	—	—	XP_005845929	XP_005539560	XP_005708234
						XP_005845928	XP_005535696	XP_005708528
						XP_005848965
Glutathione reduction	GR	g1278.t1	XP_001696579	XP_002954868	XP_005647342	XP_005845177	XP_005535272	XP_005708458
		g2017.t1	XP_001694700	XP_002946157	XP_005643099	XP_005848662
					XP_005648772
Arsenite efflux pump	ArsA	g9591.t1	XP_001702275	XP_002959195	XP_005647491	XP_005850758	XP_005537880	XP_005703923
		g9707.t1	XP_001693332	XP_002950290	XP_005649049	XP_005852082	XP_005538537	XP_005705663
							XP_005537889	XP_005708637
	ArsB	—	—	—	—	—	—	XP_005706040
								XP_005703336
	ACR3	g12377.t1	—	—	XP_005649016	—	—	—
Arsenite methylation	ArsM	g855.t1	AFS88933	XP_002954859	XP_005651832	XP_005845903	XP_005539091	XP_005706547
						XP_005847544	XP_005535535	XP_005706047
						XP_005847712
Phytochelatin synthesis	γ-ECS	g12930.t1	XP_001701647	XP_002949586	XP_005646648	XP_005844806	XP_005535934	XP_005703986
	GSS	g1014.t1	XP_001691543	XP_002955849	XP_005652117	XP_005847003	XP_005535713	XP_005706941
	PCS	g3135.t1	XP_001701021	XP_002955080	XP_005643662	XP_005845668	XP_005536287	—
		g5416.t1		XP_002953242