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Increased expression of complement pathway genes in ADRD, SFD, and DHRD compared with Ctrl hiPSC-RPE monoculture at D90. (A–C) Quantitative real-time PCR analysis demonstrated increased expression of several complement pathway genes in SFD (A), DHRD (B), and ADRD (C) hiPSC-RPE cultures at D90 compared with age-matched Ctrl hiPSC-RPE. Data are presented as mean + SEM. *P < 0.05, **P < 0.005.
