Fig. 6.

RABIF regulates a subset of related Rab GTPases. (A) Proteomic analysis of Rab expression in RABIF-KO HeLa cells. Data are presented as percentage of expression levels in WT cells. Average values of two technical replicates are shown (Rab1b levels were identical in the replicates, while Rab5a was quantified in only one replicate). (B) Immunoblots showing the expression levels of selected Rabs in the WT or Rabif-KO adipocytes. (C) Dendrogram showing the relatedness of human Rab proteins to each other. Proteins influenced by RABIF are highlighted in red. Rabs that were not influenced by RABIF are labeled in green. Rabs not detected by MS are shown in black.