TABLE 3.

Anthropometric gains from D1 to D21

	Treatment group
	n	nHMF	n	cHMF	P*
Weight gain, g · kg−1 · day−1	64	18.3 ± 3.7	67	16.8 ± 3.7	0.013†
Length gain, cm/wk	55	1.23 ± 0.62	65	1.18 ± 0.49	0.842
HC gain, cm/wk	57	1.04 ± 0.32	65	0.96 ± 0.26	0.125

cHMF = control human milk fortifier; D1 = study day 1 (first day of full-strength fortification); D21 = study day 21; HC = head circumference; nHMF = new human milk fortifier. Data are presented as unadjusted mean ± SD.

^*One-sided superiority P value based on analysis of covariance model adjusted for postmenstrual age and relevant anthropometric measure at D1, sex, and center.

^†Adjusted difference in weight gain (nHMF–cHMF): mean difference = 1.18 g · kg⁻¹ · day⁻¹; 95% CI = 0.14, 2.21.