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The Lm ESX-1 secretion system is dispensable for epithelial cell invasion and intracellular multiplication in macrophages. (A) Entry of the WT, ΔesxA, ΔesxB and ΔessC into Caco-2 and Vero cell lines. Values are expressed relative to WT values arbitrarily fixed to 100%. (B) Intracellular replication behavior of the WT, ΔesxA, ΔesxB and ΔessC strains in J774 cells. Values are mean ± SD (n = 3).
