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. 2016 Oct 20;8(6):938–958. doi: 10.1080/21505594.2016.1250995

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© 2017 The Author(s). Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 1. — In vitro BLT efficacy against P. aeruginosa. Planktonic microbial cell suspensions (10⁸ CFU/ml) were illuminated with blue light fluences ranging from 0 to 50 J/cm² (15.7 mW/cm²; λ 405 nm; duration of irradiation: 0 to 3184 sec). Fluences up to 10 J/cm² reveal sub-lethal efficacy against P. aeruginosa isolates. (A) BLT efficacy against reference wild-type P. aeruginosa strains; (B) BLT activity against drug-sensitive clinical P. aeruginosa isolates; (C) BLT activity against MDR clinical P. aeruginosa isolates. MDR, multidrug-resistant; XDR, extensively drug-resistant. The values are the means of 3 separate experiments (3 independent experiments with 3 repetitions per sample), and the bars represent the log relative error according to http://faculty.washington.edu/stuve/log_error.pdf. The test was performed for reference P. aeruginosa isolates PAO1, PA14, and PAK and clinical isolates no. 1959/o, 3146/s, 3404/p, 133/K, 23/K, 3752/sz, 153/s, 2284/p, 556/K, 4190/pA, 3109/o, and 143/p.