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. 2017 Sep 25;12:7025–7038. doi: 10.2147/IJN.S142497

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© 2017 Kandimalla et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Effect of various treatments on serum (A) IL-1β and (B) TNF-α levels. All the results are expressed as mean ± SD (n=6). ^$P<0.05, comparison of vehicle treatment with control; *P<0.05, comparison of silymarin, SGNPs, and GSGNPs treatment with vehicle treatment; ^P<0.05, comparison of SGNPs and GSGNPs treatment with silymarin treatment.

Abbreviations: IL-1β, interleukin-1β; TNF-α, tumor necrosis factor-α; SGNPs, silymarin-tethered gold nanoparticles; GSGNPs, SGNPs aggregated in glycogen.