Figure 8. The N-terminal LaM-RRM module-containing fragment of LARP4 exhibits poly(A) 3' end sensitivity.
(a, c and d) Electrophoretic mobility shift assay (EMSA) using purified recombinant LARP4-NTD (1-286) protein in varying concentrations indicated above the lanes in uM with the purified oligo-RNA species indicated in the lower part of the gels. (b and e) Quantification of binding in a, c and d, and EMSA experiments with other oligo-RNAs as indicated.