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. 2017 Oct 3;12(10):e0185944. doi: 10.1371/journal.pone.0185944

Fig 2. Combined linkage and homozygosity mapping.

Fig 2

We performed parametric linkage analysis for a recessive trait in all eight family members and homozygosity mapping across the three affected German Spitz dogs. Ten linked genome segments are indicated in orange and three homozygous segments with shared alleles are indicated in red. Only one region on chromosome 3 showed both linkage and homozygosity and was considered the critical interval (arrow). Specifically, this ~15 Mb region corresponded to Chr3:28,747,944–43,731,542 (CanFam 3.1 assembly).