Table 1. Results overview.
species | n | PA ELISA positive | PA WB positive | LF WB positive | observed seroprevalence (95% CI) | positive control | negative control | conjugate |
---|---|---|---|---|---|---|---|---|
Western red colobus monkey (Procolobus badius) |
15 | 1 | 2 | 1 | 13% (2–42%) | AVA vaccinated human | human | goat α human |
Western black-and-white colobus monkey (Colobus polykomos) | 10 | 1 | 1 | 1 | 10% (0–46%) | AVA vaccinated human | human | goat α human |
Sooty mangabey (Cercocebus atys) | 16 | 0 | 0 | 0 | 0% (0–24%) | AVA vaccinated human | human | goat α human |
Chimpanzee (Pan troglodytes verus) | 9 | 0 | 0 | 0 | 0% (0–37%) | AVA vaccinated human | human | goat α human |
Maxwell's duiker (Cephalophus maxwelli) | 9 | 4 | 0 | 0 | 0% (0–37%) | Sterne vaccinated goat | Red forest duiker (Cephalophus natalensis) from zoo | rabbit α goat |
Results for PA ELISA, PA and LF Western Blot in each tested species. Observed seroprevalence includes all PA Western Blot positive animals. The 95% confidence intervals for seroprevalence were approximated with the prop.test function in R [31].