Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 2;216(10):3275–3290. doi: 10.1083/jcb.201702177

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 MacDonald and Piper

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 6. — The Vam6-Gtr1/Gtr2-Ltv1 pathway controls recycling independently of TORC1. (A) Ste3-GFP-DUb localized with FM4-64 after a 60-min chase period in minimal medium lacking dye. (B) FM4-64 efflux of indicated mutants after 10 min. (C) Experimental framework for tracing how the multifunctional proteins Vam6, Gtr1/Gtr2, and Ltv1 work together to control recycling rather than through their other known functions in endosomal fusion (Vam6, as part of the HOPS complex), TORC1 function (Gtr1/Gtr2, stimulators of TORC1 via the Ego complex), and ribosomal biogenesis (Ltv1, as a regulator of pre40S ribosome processing). Bar, 5 µm.