Table 1. CRC, PLP and CTRL characteristics of the study population in the discovery and validation phases.
| Variables | Discovery Phase | Validation Phase | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
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| CRC, N (%) | PLP, N (%) | CTRL, N (%) | P value | CRC, N (%) | PLP, N (%) | CTRL, N (%) | P value | |
| Age( Mean, SD) | 53.97(13.46) | 51.87(10.82) | 55.23(10.46) | 0.67 | 58.66(10.28) | 57.72( 9.21) | 57.92( 9.91) | 0.71 |
| BMI( Mean, SD) | 28.09( 5.20) | 27.92( 5.77) | 28.32( 6.18) | 0.87 | 30.25( 5.61) | 27.43( 5.58) | 28.37( 8.67) | 0.21 |
| Sex | ||||||||
| Male | 18(60.00) | 18(60.00) | 18(60.00) | 23(46.00) | 23(46.00) | 23(46.00) | ||
| Female | 12(40.00) | 12(40.00) | 12(40.00) | 1 | 27(54.00) | 27(54.00) | 27(54.00) | 1 |
| Smoking status | ||||||||
| Never | 16(53.33) | 20(66.67) | 13(43.33) | 31(62.00) | 28(56.00) | 30(60.00) | ||
| Former | 10(33.33) | 8(26.67) | 7(23.33) | 15(30.00) | 19(38.00) | 15(30.00) | ||
| Current | 4(13.33) | 2(6.67) | 10(33.33) | 0.07 | 4(8.00) | 3(6.00) | 5(10.00) | 0.86 |
| Smoker | ||||||||
| Ever | 14(46.67) | 10(33.33) | 17(56.67) | 19(38.00) | 22(44.00) | 20(40.00) | ||
| Never | 16(53.33) | 20(66.67) | 13(43.33) | 0.19 | 31(62.00) | 28(56.00) | 30(60.00) | 0.82 |
| BMI | ||||||||
| <25 | 6(26.09) | 9(32.14) | 15(50.00) | 7(15.91) | 13(37.14) | 25(50.00) | ||
| ≥25 | 17(73.91) | 19(67.86) | 15(50.00) | 0.16 | 37(84.09) | 22(62.86) | 25(50.00) | <0.01 |
CRC, colorectal cancer; PLP, adenoma polyp; CTRL, control; SD, standard deviation; BMI, body mass index