TP53 autoantibody titers and CA125 values in serum samples from the UKCTOCS screening trial. A, Box plots for TP53 autoantibody and CA125. Each box exhibits maximum, upper quartile, median, lower quartile and minimum values. Triangles represent cases and circles represent controls. The lower table displays TP53 autoantibody positive numbers and percentages in ROCA/CA125 (+) case, ROCA/CA125 (-) case and control groups. B, Scatter plots of TP53 autoantibody levels and CA125 values. Triangles represent ovarian cancer cases and circles represent controls. The black dashed line represents the common cut-off value (78 U/mL) for TP53 autoantibody.