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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Cancer Res. 2017 Jul 31;77(19):5349–5359. doi: 10.1158/0008-5472.CAN-17-0061

Table 1.

Gene set overlap analysis comparing cancer hallmark gene sets and oncogenic signature gene sets to genes upregulated in Tcon versus Dcon-Ecad het stomachs.

Name Description FDR q-value
Cancer Hallmark Gene Sets
HALLMARK_KRAS_SIGNALING_UP Genes up-regulated by KRAS activation. 3.36e−61
Oncogenic Signature
KRAS.600_UP.V1_UP Up-regulated in four lineages of epithelial cell lines over-expressing oncogenic KRAS 1.47e−19
KRAS.DF.V1_UP Up-regulated in epithelial lung cancer cell lines over-expressing oncogenic KRAS 9.39e−18
KRAS.600.LUNG.BREAST_UP.V1_UP Up-regulated in epithelial lung and breast cancer cell lines over-expressing oncogenic KRAS 2.68e−17
KRAS.LUNG.BREAST_UP.V1_UP Up-regulated in epithelial lung and breast cancer cell lines over-expressing oncogenic KRAS 2.55e−15
KRAS.BREAST_UP.V1_UP Up-regulated in epithelial breast cancer cell lines over-expressing oncogenic KRAS 4.49e−11
KRAS.LUNG_UP.V1_UP Up-regulated in epithelial lung cancer cell lines over-expressing oncogenic KRAS 1.34e−10
KRAS.300_UP.V1_UP Up-regulated in four lineages of epithelial cell lines over-expressing oncogenic KRAS 8.06e−09
KRAS.PROSTATE_UP.V1_UP Up-regulated in epithelial prostate cancer cell lines over-expressing oncogenic KRAS 2.75e−08
KRAS.50_UP.V1_UP Up-regulated in four lineages of epithelial cell lines over-expressing oncogenic KRAS 2.78e−07