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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Cancer Res. 2017 Jul 31;77(19):5349–5359. doi: 10.1158/0008-5472.CAN-17-0061

Table 2.

Gene set overlap analysis comparing transcription factor target gene sets and oncogenic signature gene sets to genes up-regulated in Tcon vs Dcon-Ecad het stomachs.

Name Description FDR q-value
Transcription Factor Target Gene Sets
CTTTGT_V$LEF1_Q2 Genes with promoter regions containing the LEF1 motif 3.27 e−87
CAGGTG_V$E12 Q6 Genes with promoter regions containing the TCF3 motif 1.44 e−58
Oncogenic Signature Gene Sets
LEF1_UP.V1_UP Upregulated in DLD1 cells over-expressing LEF1 2.86 e−19
WNT_UP.V1_UP Upregulated in C57MG cells over-expressing WNT1 1.42 e−8
BCAT.100_UP.V1_UP Upregulated in HEK293 cells expressing active CTNNB1 3.83 e−8