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Deletion of Sin3b does not impair loss of PTEN-driven AKT activation. A, Representative images of immunohistochemistry for SIN3B on paraffin sections of the dorsolateral lobe of prostates taken from three-month-old Sin3bpc+/−, Sin3bpc−/−, Sin3bpc+/− Ptenpc−/−, and Sin3bpc−/− Ptenpc−/− mice. B, PTEN. C, pAKT. Top Panel = 10× magnification. Bottom Panel = 40× magnification. Scale bar = 200 μm. n = 3 for each genotype.
