Table 3.

Test Characteristics for PEth to detect any alcohol misuse and severe alcohol misuse (AUDIT and AUDIT-C)

Estimate, % (95% Confidence Interval)	Sensitivity	Specificity	Positive predictive value	Negative predictive value
PEth ≥ 250 ng/mL	AUDIT any level of alcohol misuse (≥8 for men, ≥5 for women)
All Groups* (n=122)	87.3 (76.0, 94.0)	88.1 (76.5, 94.7)	88.7 (77.5, 95.0)	86.7 (74.9, 93.7)
ICU group (n=33)	66.7 (35.4, 88.7)	95.2 (74.1, 99.8)	88.9 (50.7, 99.4)	83.3 (61.8, 94.5)
PEth ≥ 400 ng/mL	AUDIT severe alcohol misuse (≥16 for men, ≥13 for women)
All Groups* (n=122)	89.8 (77.0, 96.2)	87.7 (77.4, 93.9)	83.0 (69.7, 91.5)	92.8 (83.2, 97.3)
ICU group (n=33)	71.4 (30.3, 94.9)	96.2 (78.4, 99.7)	83.3 (36.5, 99.1)	92.6 (74.2, 98.7)
PEth ≥ 250 ng/mL	AUDIT-C any level of alcohol misuse (≥4 for men, ≥3 for women)
All Groups* (n=122)	80.6 (69.2, 88.6)	91.7 (79.1, 97.3)	93.5 (83.5, 97.9)	75.9 (62.5, 85.7)
ICU group (n=33)	66.7 (35.4, 88.7)	94.7 (71.9, 99.7)	88.9 (50.7, 99.4)	81.8 (59.0, 94.0)
PEth ≥ 400 ng/mL	AUDIT-C severe alcohol misuse (≥8 for men, ≥6 for women)
All Groups* (n=122)	83.6 (70.7, 91.8)	89.2 (78.5, 95.2)	86.8 (74.0, 94.1)	86.6 (75.5, 93.3)
ICU group (n=33)	66.7 (24.1, 94.0)	92.0 (72.5, 98.6)	66.7 (24.1, 94.0)	92.0 (72.5, 98.6)

^*Burn and medical intensive care unit patients, inpatient alcohol detoxification patients, and control group.