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Three dimensional structure of PSD-95 PDZ3 domain (pdb code 1BE9) in complex with a peptide ligand, YKQTSV. The conserved structure of PDZ domains is colored in grey, the additional C-terminal α-helix is highlighted in blue and the backbone of the peptide is colored in red. Residue number 337, which was mutated into Trp as a probe for fluorescence monitored folding studies, is highlighted in sticks.
