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. 2017 Oct 3;7:12644. doi: 10.1038/s41598-017-13011-0

Figure 2.

Figure 2

Poliovirus neutralising antibody responses to (a) IPV1, (b) IPV2 and (c) IPV3 following triple monovalent vaccination. Vaccine doses used were a standard human dose 40:8:32 DU, DU, for types 1, 2, and 3, respectively), ~1/8th of the human dose (5.9:1.3:5.2 DU) and 1/40th of the human dose (1.3:0.17:0.89 DU). A positive response is defined as a neutralising titre ≥3.0 log2 (dotted line). Each symbol represents a single animal, with the line indicating the median titre. * and ** indicates a statistically significant difference between dose matched Nanopatch and IM group as assessed by one-way ANOVA (alpha level 0.05) with a Sidak post test of p = <0.05 and p = <0.01, respectively.