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. 2017 Jul 12;118(4):1998–2008. doi: 10.1152/jn.00270.2017

Fig. 3.

Fig. 3.

LTP Induction of nonspecific electrical and identified RMTg-specific optical IPSCs. A: electrical induction. RMTg-specific IPSCs showed no potentiation following induction by high-frequency stimulation (HFS; n = 5 cells, P = 0.375), even though paired electrical IPSCs during the same recordings successfully expressed LTP (n = 5 cells, P = 0.002). B: agonist induction. RMTg-specific IPSCs showed no potentiation following bath application of an activator (BAY 41-2272; 10 µM) for the enzyme in the synthesis of GTP to cyclic GMP, soluble guanylyl cyclase (sGC; n = 11 cells, P = 0.227). However, unpaired electrically induced IPSCs successfully expressed LTP (n = 10 cells, P = 0.001).