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. 2017 Sep 8;7:42–49. doi: 10.1016/j.omtm.2017.09.002

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Effect of rAAV2/9-DES-hGAA Treatment on ³¹P MRS PME Resonances In Vivo and ¹H HR-MAS Glucose-6-Phosphate in Isolated Muscles

Both in vivo PME levels and glucose-6-phosphate levels from intact muscles were significantly elevated in Gaa^−/− mice compared to control. rAAV2/9-DES-hGAA induced a significant decrease in both PME (A) and glucose-6-phosphate (B). Data are presented as individual data points and box plots indicating the lower and upper quartiles and the median. The bars indicate the minimum and maximum values. *p < 0.05; **p < 0.005.