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. 2017 Aug 16;4(3):419–437. doi: 10.1016/j.jcmgh.2017.08.002

Figure 3.

Figure 3

Ex vivo mucosal and systemic homing phenotypes of CD8+ T cells following Ty21a oral vaccination. (A) Ex vivo percentages of integrin α4β7+ cells were evaluated in TI-LPMC and PBMC CD8+ T cells isolated from biopsies and blood of Ty21a-vaccinated (n = 13; red symbols) and unvaccinated (n = 22; black symbols) volunteers. (B) Ex vivo percentages of CCR9+, (C) integrin α4β7+CCR9+, and (D) CCR6+ cells were determined in TI-LPMC and PBMC CD8+ T cells isolated from biopsies and blood from Ty21a-vaccinated (n = 5; red symbols) and unvaccinated (n = 5; black symbols) volunteers. Significant differences between TI-LPMC and PBMC in vaccinated and unvaccinated volunteers are denoted as *P < .05 and **P < .005. Median values for each group are denoted as horizontal black bars.