Figure 7.

S Typhi–specific responses of terminal ileum LPMC CD8⁺ T_CM and T_EMRA subsets in healthy adults following oral Ty21a immunization. The net percentages of S Typhi–specific responses (IFN-γ, TNF-α, IL2, IL17A, MIP-1β, and CD107a) in CD69⁺CD8⁺ T_CM (A) and CD69⁺CD8⁺ T_EMRA (B) subsets were compared between Ty21a-vaccinated (n = 13; red symbols) and unvaccinated volunteers (n = 22; black symbols) with significant differences (*P < .05) indicated. Horizontal black bars represent median values.