Table 5.

Studies reporting Alemtuzumab-related thyroid dysfunction.

Reference	No. of patients	No. of patients who developed thyroid dysfunctions	Thyroid function
Coles et al. (39)	27	9/27 (33%)	Hyperthyroidism: 9 (33%)a
Coles et al. (41)	216a	49/216 (22.7%)	Hyperthyroidism: 32 (14.8%)
			Hypothyroidism: 15 (6.9%)
Coles et al. (2)	596	100/596 (16.7%)	Hyperthyroidism: 28 (4.7%)
			Hypothyroidism: 31 (5.2%)
Cohen et al. (1)	376	68/376 (18%)	Hyperthyroidism: 28 (7%)
			Hypothyroidism: 18 (5%)
Tuohy et al. (45)	87	35/87 (41%)	Hyperthyroidism: 22 (25.3%)
			Hypothyroidism: 12 (13.8%)

^aOne patient developed hypothyroidism before shifting to hyperthyroidism.