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Pharmacokinetic measurements for TC299423. (A) Concentrations of TC299423 in plasma (ng/mL) following ip (0.3 mg/kg) and oral (1 mg/kg) administration. (B) Concentrations of TC299423 in the brain (ng/g) following ip (0.3 mg/kg) and oral (1 mg/kg) administration. All data are mean ± SEM. n = 3 mice. See text for conversion of ng/ml to μM.
