FIG 1.
Adenosine catabolism in Pseudomonas aeruginosa. Nuh, the PA0143 gene product, is a nucleosidase that can cleave the base from adenosine or inosine to release ribose (31, 33). PA0148 is involved in the deamination of adenine (35). PA0148 cannot catalyze the deamination of adenosine (35) and there is no gene known to encode an adenosine deaminase in P. aeruginosa. Hypoxanthine is metabolized in multiple reactions to urea (31).