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. 2017 Sep 26;8:1851. doi: 10.3389/fmicb.2017.01851

Figure 1.

Figure 1

CRISPR-Cas systems in Bifidobacterium longum. Number of CRISPR-Cas systems detected in B. longum strains for each CRISPR-Cas type (A). Comparison between the occurrence and diversity of CRISPR-Cas systems in B. longum strains (outside ring) and Bifidobacterium (inside ring). Percentage was calculated based on the number of positive strains for each subtype divided by total strains analyzed in each study (B). Phylogenetic tree based on the amino acid sequence of Cas1 protein of B. longum and other bifidobacteria species, aligned with MUSCLE algorithm, and depicted with UPGMA using 500 bootstrap replicates. Bootstrap values are recorded on the nodes. The CRISPR-Cas subtypes are written on the right and groups are colored for each subtype (C).