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CRISPR phylogenetic analyses in B. longum. Phylogenetic tree based on the Cas1 protein of B. longum strains (A), Cas9 protein (B), Cas3 protein (C), and the CRISPR repeats sequence (D). Alignments were performed with MUSCLE algorithm and the tree was depicted with UPGMA using 500 bootstrap replicates. Bootstrap values are recorded on the nodes. The CRISPR-Cas subtypes are written on the right and groups are colored for each subtype.
