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. 2017 Sep 27;8:684. doi: 10.3389/fphar.2017.00684

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Copyright © 2017 Zhou, Peng, Bu, Liu, Sun and Liao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plots of ex vivo AUC/MIC ratios versus the change of bacterial counts between 0 and 12 h (log₁₀ CFU/mL) against S. suis ATCC 43765 in the porcine serum. The line represents the curve of predicted values based on the sigmoid E_max equation, and the points represent serum samples collected at time points from 0 to 360 h.