Table 3.

Detailed results of non-pneumococcal streptococcal strains generating false positive signals when tested in molecular assays for common pneumococcal molecular targets.

	lytA	piaB	ply	cpsA	Spn9802	zmpCb (560 bp)	zmpC (5 kb)	zmpC (8 kb)	qPCR serotype
strains from invasive diseasea
S. dysgalactiae subsp. equisimilis			+
S. equi subsp. zooepidemicus						+
S. mitis (n = 4)			+
S. mitis			+						19F
S. oralis					+
S. oralis				+
S. pseudopneumoniae					+
S. pseudopneumoniae (n = 2)			+		+
strains from asymptomatic carriagea
S. infantis									9A/N/V
S. infantis						+	+
S. infantis (n = 2)						+
S. mitis									5
S. mitis									18B/C
S. mitis									19F
S. mitis			+			+
S. mitis			+			+	+
S. mitis (10 strains)			+
S. oralis						+
S. pseudopneumoniae			+

^aStrains annotated based on sequence analysis of the ribosomal S2 gene.

^bStrains which generated PCR amplicons with full homology to sequence published for S. pneumoniae.