Table 4.
Streptococcus pneumoniae strains non-typeable (thus, unencapsulated) by the conventional diagnostic method, positive when tested in molecular assays for common pneumococcal molecular targets.
| number of isolates | lytA | piaB | ply | cpsA | Spn9802 | zmpCa (560 bp) | zmpC (5 kb) | zmpC (8 kb) | qPCR serotype | CST serotype |
|---|---|---|---|---|---|---|---|---|---|---|
| 9 | + | + | + | + | ||||||
| 3 | + | + | + | |||||||
| 1 | + | + | + | + | + | |||||
| 1 | + | |||||||||
| 1 | + | + | + | + | + | 22A/F | 22F | |||
| 1 | + | + | + | + | + | 25F | ||||
| 1 | + | + | + | + | 19A | 19A | ||||
| total n (%) | 17 (100) | 3 (18) | 15 (90) | 3 (18) | 7 (40) | 10 (59) | 10 (59) | 0 (0) | 2 (12) | 3 (18) |
aStrains which generated PCR amplicons with full homology to sequences published for S. pneumoniae.