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. 2017 Sep 6;7(9):170129. doi: 10.1098/rsob.170129

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© 2017 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 4. — Summary of neuropeptide precursors identified in Ophionotus victoriae, Amphiura filiformis and Ophiopsila aranea. Neuropeptide precursors are classified based on the type of G-protein coupled receptor (GPCR) their constituent peptides are predicted to activate (see Mirabeau and Joly [6]). Some peptides bind to receptors other than GPCRs and these are grouped with peptides where the receptor is unknown. Ophiuroids have neuropeptide precursors from up to 32 families. The number of putative mature peptides derived from each precursor has been indicated along with the presence of amidation and pyroglutamation.