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. 2017 Oct 4;7:12694. doi: 10.1038/s41598-017-12137-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Upstream region and putative transcription factor binding sites of ALFPm gene. The genomic sequence of the 5′-upstream region of the ALFPm3 (a) and ALFPm6 (b) genes. The putative cis-regulatory elements in the 5′-flanking promoter region are underlined. The transcription start site (+1) is indicated by the arrow labelled +1. The start codon and TATA box are also indicated, and their sequences are bolded. Schematic diagrams of the ALFPm3 (c) and ALFPm6 (d) promoter constructs used to delineate the TF-binding sites are shown.