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. 2017 Oct 4;7:12649. doi: 10.1038/s41598-017-12650-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Western blot detections of protein changes in ametropic chick vitreous (mean ± standard deviation). The ratios in LIM and LIH were first normalized by their fellow control eyes (expressions in monocular myopia or hyperopia over control eyes). Expression changes of ApoA1 and ovotransferrin were significantly increased after −10D lenses inducement for 3 days, compared to +10D lenses inducement (*p < 0.05, paired t-test). No significant differences were detected after treatment for 7 days (p > 0.05).