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. 2017 Oct 3;113(7):1520–1530. doi: 10.1016/j.bpj.2017.07.033

Figure 5.

Figure 5

(A) (Top) Given here are mean g-ratio values versus the EAE score (see Fig. S5). (Bottom) Given here are S2 values versus different scores of EAE, for the myelin regions of normal morphology (see text). Statistical analysis is shown relative to the control sample except when notified with a bar (∗, p ≤ 0.05, ∗∗, p ≤ 0.01, ∗∗∗, p ≤ 0.001). Given is the number of regions considered in the analysis: control (N = 26), CFA (N = 30), score 0 (N = 28), score 1 (N = 17), score 1.5 (N = 9), score 2 (N = 22), score 2.5 (N = 19), score 4 (N = 11). Error bars are SD values. (B) Shown here are (S2, S4(s)) values for myelin at different EAE scores (straight myelin sheaths are considered, and only the most statistically relevant scores are depicted for clarity) and MLVs from different lipid/cholesterol compositions: pure DPPC/Chol or DOPC/Chol at 0, 5, 10, 20% (v/v), or DPPC/DOPC/Chol 30% (v/v/v) ternary mixtures with DPPC/DOPC ratios 1:1; 1:2; 2:1. Error bars are SD values (for MLV samples N = 4). To see this figure in color, go online.