Skip to main content
. 2017 Jul 29;79(9):1472–1479. doi: 10.1292/jvms.17-0180

Table 2. Combined effects of cefazolin (CEZ) and nisin A determined by the checkerboard assay.

Organism n FIC index No. of strains (%)
Synergism Additive Indifferent Antagonism
(≤0.5) ( >0.5 to ≤1.0) ( >1.0 to ≤2.0) ( >2.0)
Staphylococcus aureus 20 0.19–0.5 20 (100) 0 (0) 0 (0) 0 (0)
Staphylococcus intermedius 20 0.19–1.0 8 (40) 12 (60) 0 (0) 0 (0)
Streptococcus agalactiae 10 0.63–1.0 0 (0) 10 (100) 0 (0) 0 (0)
Streptococcus dysgalactiae 18 0.56–1.0 0 (0) 18 (100) 0 (0) 0 (0)
Enterococcus faecalis 18 0.19–1.0 13 (72.2) 5 (27.8) 0 (0) 0 (0)
Escherichia coli 18 0.5 –1.0 4 (22.2) 14 (77.8) 0 (0) 0 (0)

The FIC index values were interpreted as follows: ≤0.5, synergistic; >0.5 to ≤1.0, additive; >1.0 to ≤2.0, indifferent; and >2.0, antagonistic effects.