Fig. 2. Real-time observation of PcCDH anchored on the gold surface by HS-AFM. Time-evolution of the domain motion of PcCDH in a different concentration of cellobiose (0 and 150 μM, Movies S1 and S4†). Estimated relative positions of the DH domain (orange) and the CYT domain (green) are illustrated on the right side of each set of image frames.