Table 5.
Sum 35PCBs, subsets and individual PCB congeners (ng/g wet weight) and metabolic syndrome; unadjusted and adjusted logistic regression models with odds ratios (OR) and 95% confidence intervals (CI).
| PCBs | MetSyn n (%) |
Unadjusted OR (95% CI) |
Adjusteda OR (95% CI) |
Adjusteda & Lipidsb OR (95% CI) |
|---|---|---|---|---|
| Σ35PCBs Quintiles (ng/g whole weight) | 247 (50%) | |||
| Q1. 0.11–1.15 | 46 (37%) | 1.00 (Reference) | 1.00 (Reference) | 1.00 (Reference) |
| Q2. 1.16–2.42 | 52 (54%) | 1.98 (1.15–3.40) | 1.12 (0.51–2.46) | 0.94 (0.42–2.12) |
| Q3. 2.43–4.33 | 44 (49%) | 1.60 (0.92–2.78) | 0.69 (0.30–1.58) | 0.49 (0.21–1.17) |
| Q4. 4.34–9.33 | 55 (53%) | 1.88 (1.11–3.19) | 0.81 (0.33–1.98) | 0.57 (0.22–1.44) |
| Q5. 9.34–170 | 50 (59%) | 2.39 (1.36–4.21) | 0.78 (0.27–2.21) | 0.51 (0.17–1.50) |
| Log10 Σ35PCBs per 1 ng/g increase | 247 (50%) | 1.83 (1.32–2.53) | 1.11 (0.57–2.16) | 0.78 (0.39–1.54) |
| Log10 ΣDioxin-Like (#105, 118, 156, 157, 167, 189) per 1 ng/g increase | 247 (50%) | 1.94 (1.40–2.68) | 0.96 (0.51–1.78) | 0.74 (0.39–1.40) |
| Log10 ΣNon Dioxin-Like (#138, 153, 170, 180, 187) per 1 ng/g increase | 247 (50%) | 1.74 (1.27–2.39) | 1.09 (0.58–2.06) | 0.79 (0.41–1.52) |
| Log10 PCB congeners Each per 1 ng/g increase | ||||
| #28 | 247 (50%) | 2.50 (1.54–4.05) | 1.18 (0.61–2.26) | 0.86 (0.43–1.70) |
| #66 | 247 (50%) | 1.93 (1.42–2.63) | 1.01 (0.63–1.61) | 0.86 (0.53–1.38) |
| #74 | 247 (50%) | 2.90 (2.08–4.05) | 1.29 (0.70–2.39) | 0.82 (0.43–1.58) |
| #99 | 247 (50%) | 1.62 (1.25–2.11) | 0.89 (0.56–1.40) | 0.72 (0.45–1.15) |
| #118 | 247 (50%) | 1.93 (1.50–2.48) | 0.95 (0.61–1.50) | 0.80 (0.50–1.28) |
| #153 | 247 (50%) | 1.69 (1.29–2.21) | 0.91 (0.55–1.52) | 0.68 (0.40–1.15) |
| #156 | 247 (50%) | 2.01 (1.50–2.69) | 1.29 (0.74–2.26) | 0.84 (0.46–1.51) |
| #170 | 247 (50%) | 1.84 (1.38–2.45) | 1.23 (0.70–2.15) | 0.79 (0.44–1.44) |
| #187 | 247 (50%) | 1.55 (1.21–1.98) | 0.91 (0.57–1.46) | 0.67 (0.41–1.10) |
| #194 | 247 (50%) | 1.58 (1.24–2.02) | 1.19 (0.74–1.92) | 0.81 (0.48–1.34) |
| #206 | 247 (50%) | 1.81 (1.42–2.31) | 1.28 (0.79–2.08) | 0.89 (0.54–1.48) |
| #209 | 247 (50%) | 1.71 (1.38–2.11) | 1.14 (0.72–1.79) | 0.82 (0.52–1.32) |
a
Adjusted for age in yrs, family hx heart disease (no/yes), family hx diabetes (no/yes), liver disease (no/yes), sex, race (white/nonwhite), alcohol consumption (none, light/moderate, heavy/binge), current smoker (no/yes), marital status (not married, yes spouse/partner), grade (1–6 as interval; none to college grad), BMI (continuous).
b
Total lipids (continuous) added to the adjusted models.